If you have mouse input problems.. vsync might be the reason.. there are basicly three modes you can choose from:
- no vsync: as said it renders as many frames as possible, high usage of cpu/gpu and produces tearing because the frames are not synced
- vsync with double buffering: prevents tearing but a problem arises IF your computer dips under the sync rate. Lets asume its 60hz, if fps do down to 55fps, the syncing causes fps to instead go down to 30fps and reuse each frame twice. That huge fps drop can be very evil but with the new engine in 2.3 and some tweaks that should never happen.
-vsync with triple buffering:prevents tearing but because of the three buffers it uses even more graphics ram and the three buffers also cause a slight input lag as it will display one old frame, wait to display the second buffer and render the new frame with the input action into the third buffers which can give you up to 3 frames input lag. Maybe try to disable the triple buffering in the video drivers.
http://en.wikipedia.org/wiki/Triple_Buffering