It's always good to have Nexuiz (not "Nexiuz", like on your site) on as many platforms as possible - so go ahead
I assume such a homemade console could work and sell a few units (if you're homebrew friendly -I guess you are - and doing good PR). After all there are units like the GP2X with a similiar "hacker friendly" approach. Just make sure you can survive a possible commercial failiure. And if you sell a few units keep in mind you have to give support, too (if a console fails you'll have to replace it - this may cost many bucks, depending on how reliable your hardware is).
However, everything has to work "out of the box" to give a true "console" experience. Plus having a real web site would help (using freewebs doesn't transport the message that people should give you their money very well; having a "cool" stylish design would help, too). Make sure you don't ask questions like "How do you like my site" if you want to establish a business connection with your clients. Make clear what they are registering for (Usually *I* don't register if I get nothing in return). Talk less about what parts you use - talk about what games will run atop of it and how it'll look fantastic and how it'll improve our livestyle.
If you're serious with this make sure to assemble a team: Someone for a really cool webpage, someone who has an idea how business works, someone with the technical background etc. etc.
Oh, and make sure you keep patents etc. in mind. Your hardware would allow you to play DVDs - but the MPEG codecs are patented and you'll be in really serious trouble (with lawsuit and all) if you'd sell your consoles with MPEG codecs installed without paying for them (That's why there are really free codecs like Ogg Vorbis (Nexuiz uses it) for audio and Ogg Theora for video). Using open source MPEG codecs e.g. won't protect you from patent infringement (copyright - that's what Open Source licenses usually handle - has nothing to do with patents).
To put it into a nutshell: I wish you the best of luck. Make sure you don't end up in serious trouble and plan your business well.