To do that, you may need to check all the phisics on the engine and on the mod and replace all code that asume down is '0 0 -1' to whatever down can be. I guest nowdays down is hardcoded, but can be modified. And ...welll.. I dont know much about how the prediction on Nexuiz is coded, but you may need to inform the prediction about this change trough the netcode, changes on netcode are always ugly often break things.
Also the way the player send back movements may need changes, etc. Is a huge change, feasible but boring to do, something that needs lots of changes, testing, changes, testing, changes, testing, more changes, more testing, and more changes, and more debugging, and more changes, more debugging and finally lots of betatesting. And still will have bugs. But I think is feasible, only a really boring feature to code.