Basically - 2.2.3 seems to have the same problems as 2.2.2: I get a black screen with sound. I can click around in the darkness to enter menus that are also dark, and if I'm lucky, I'll click the right combos that'll get me into a server, after which the game plays normally.
That's the SDL version.
The non-SDL version seems to work normally, except 1) The keypad isn't mapped, which is bad since that's where I've got my controls, and 2) some of the projectiles don't show (such as the bouncy blue balls). There are also some odd visual artifacts on the screen.
I tried using the OS X build that was uploaded here some time ago, but it just told me to go to use the console to locate the files needed to play - even though the engine was in the Nexuiz folder.
But 2.2.1 still seems to be compatile with the servers, so I'll just keep on playing that and all is well. But I do worry that there will be a future Nexuiz build that breaks that compatibility and does not work on the mac.