I know this issue is an old chestnut, but it's happening to me. The sdl version of the game works fine, but plain old nexuiz.exe crashes every time.
I'm using a Dell Inspiron 9400 laptop with an ATI Radeon Mobility X1400 GPU, with Catalyst Control 2007.0928.2231.38404 - that's the latest version I am able to download.
The crash report says "Appname nexuiz.exe AppVer 1.0.0.0 ModName msvcrt.dll ModVer 7.0.2600.2180 Offset 00037c7e"
Sometimes, however it says instead "AppName: nexuiz.exe AppVer: 1.0.0.0 ModName: atioglxx.dll ModVer: 6.14.10.6956 Offset: 002c4d6f"
I have the latest drivers, as I say, and I have the hotfix which hasn't fixed anything - what can I do?
Version 2.3 works fine, as does 2.4 SDL.
EDIT: I seem to have fixed it by opening nexuiz-sdl.exe, disabling OpenGL 2.0 and then re-opening Nexuiz.exe.
Odd.